# Corticotropin-Releasing Factor (CRF) Also known as the [[Stress Master Switch]]. Once released, it causes a series of physical and mental reactions - CRF spreads to the [[Amygdala]] making us sweat, making our heart race and our stomach clench - CRF also causes adrenal glands to release cortisal (stress hormone) and adrenalin - It also causes the enteric nervous system to divert energy away from digestion - This causes the stomach to slow down or even reverse - This also causes the intestines to speed up - Blood flow is diverted to the muscles and away from the gut, meaning it gets deprived of oxygen - This can quickly push you to go to the toilet